Tiny tug of war in cells underpins life









































TUG of war could well be the oldest game in the world. Cells use it for division, and now researchers have measured the forces involved when an amoeba plays the game.












Hirokazu Tanimoto and Masaki Sano at the University of Tokyo, Japan, studied what happens during the division of Dictyostelium - a slime mould that has barely changed through eons of evolution. The amoeba uses tiny projections or "feet" to gain traction on a surface.












The pair placed the amoeba on a flexible surface embedded with fluorescent beads. They used traction force microscopy to measure how the organism deformed the pattern of beads: the greater the deformation, the greater the force.












Dictyostelium normally exerts a force of about 10 nanonewtons when it moves, but the pair found this roughly doubles during division. That's because the cell uses its feet to pull itself in opposite directions, as if playing tug of war with itself.












The forces involved are about 100 billion times smaller than those used in the human form of the game, Tanimoto says (Physical Review Letters, in press).


















































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Myanmar team on 5-day visit to study S'pore's development






SINGAPORE: A ministerial delegation from Myanmar will be in Singapore for a five-day study visit.

The delegation, which will be here from 3 December, will focus on industrial policies, industrial park development, as well as technical and vocational education and training.

The Ministry of Foreign Affairs (MFA) said on Sunday that the study visit is part of Singapore's technical assistance to Myanmar, under the Singapore-Myanmar Technical Cooperation Programme.

It said Singapore is sharing its expertise and experience as part of the broader commitment to support Myanmar's efforts in reforms.

Singapore also contributes in a concrete way to Myanmar's development and the strengthening of bilateral ties.

The delegation is led by Union Minister in the President's Office and Chairman of the Myanmar Investment Commission, Soe Thane.

It'll call on Prime Minister Lee Hsien Loong and will be hosted to dinner by Emeritus Senior Minister Goh Chok Tong.

- CNA/ck



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McAfee nabbed? His blog says maybe, following CNN interview



The bizarre real-life potboiler concerning on-the-lam antivirus-software pioneer John McAfee continued today, as -- following a cloak-and-dagger CNN interview with the fugitive -- McAfee's own blog posted an item saying he may have been captured at the Belize-Mexico border.


The item, pictured above and reported earlier by news agency AFP, says little more than that and calls the report of the capture "unconfirmed." We'll update this post -- or link to a new, separate story -- when we know more. (Editor's note: See bottom of story for updates.)



Earlier, CNN managed to track McAfee down for an on-camera interview somewhere in his longtime country of residence, Belize -- where he's in hiding after his neighbor was shot to death. A CNN article accompanying an online video of the interview says its reporter had to provide a secret password and partake in a secret-agent-like, twisting-and-turning
car ride to get to the millionaire turned mystery man.


In the brief interview, which you can check out here, McAfee says, "I will certainly not turn myself in, and I will certainly not quit fighting. I will not stop my blog." He says he'll either get arrested or get away and clarifies that "Get away doesn't mean leave the country. It means they will, No. 1, find the murderer of Mr. Faull and, No. 2, the people of this country -- who are by and large terrified to speak out -- start speaking out,"


McAfee has been on the run since November 12, when his neighbor Gregory Faull was discovered with a bullet in his head. McAfee and Faull had reportedly had run-ins with each other over McAfee's dogs and armed security guards. In an interview with Wired that same day, McAfee said he thought the killers had actually been looking for him and not Faull.


Other aspects of the tale include the fact that the 67-year-old McAfee's home was raided in May and that police said they found multiple unlicensed firearms and McAfee with a 17-year-old girl. They also said he was manufacturing an antibiotic in his home without a license. McAfee's blog provides another unusual twist. Apparently begun about a week after Faull's murder, it includes entries from McAfee himself about his flight. In one such post, McAfee writes that he is traveling with a 20-year-old woman named Samantha, whom he credits with helping to keep him fed, clothed, and in hiding:



"She has also helped me evade detection by grabbing me and kissing me, in public, in a fashion that causes passerby's to feel embarrassment at the thought of staring and by creating emotional scenes that cause the curious to momentarily forget what they were looking for," he wrote. "She is acutely aware of her surroundings and is as street smart as a sober hobo."


Today's CNN report noted that police in Belize have said they don't consider McAfee a suspect in the killing; they want him only for questioning. The news agency also noted that McAfee maintains that his troubles began when he refused to bribe a government official and that he will be killed if he's arrested.


Again, the post on McAfee's whoismcafee.com/The Hinterland blog says the report of McAfee's capture is unconfirmed, so it remains to be seen if it turns out to be true. If nothing else, however, the post adds yet another chapter to this strangely unfolding tale.


Update, December 2 at 12:23 a.m. PT:
Peter Delevett at the San Jose Mercury News' SiliconBeat blog is reporting that McAfee has not been apprehended and is still on the run.


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Photos: Kilauea Lava Reaches the Sea









































































































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Wikileaks Case: Guards Deny Intimidating Manning


gty bradley manning dm 121108 wblog Bradley Mannings Former Guards Testify About Controversial Incident

(Brendan Smialkowski/AFP/Getty Images)


Bradley Manning’s former guards testified today that they did not intimidate the man accused of leaking hundreds of thousands of classified cables to the anti-secrets website Wikileaks during  a Jan. 18, 2011 incident that resulted in Manning being placed on a temporary suicide risk watch.


Manning’s attorneys cite the event as a key reason why his pre-trial confinement at the Marine brig in Quantico, Va., was unlawful and warrants the dismissal of the charges against him.


Manning faces life imprisonment on charges that he leaked the classified military and diplomatic cables to Wikileaks.  Details of those charges will come at a trial scheduled for February and are not being discussed at this week’s hearing, which is focused on his nine-month confinement at Quantico from July 2010 to April 2011.


On Jan. 18, 2011 Manning was being moved to his daily “recreation call” in a room at the brig when he experienced an apparent anxiety attack.  Manning said Thursday the guards escorting him seemed to have an aggressive attitude that made him feel nervous and ultimately feel faint.


Manning testified Thursday that he “lost my demeanor” during a later discussion with brig officials about the incident that led them to place him on temporary suicide risk watch.


Former Marine guards Lance Corporal Joshua Tankersly and Lance Corporal Jonathan Cline testified today that Manning had been moving around while his hand and leg restraints were placed on him for the escort to the exercise room.  They said they reminded Manning that he should respond properly to their orders by referring to their ranks when he answered them.


When Manning entered the recreation room they described a situation in which Manning fell backwards and landed on his backside.


They then said that when out of his leg restraints Manning ran to a weightlifting machine, hid behind it and began to cry.  Both Cline and Tankersly said they could not explain Manning’s behavior.  Both guards were ordered to leave the room and were replaced by two other guards who escorted Manning back to his cell.


Cline said he was puzzled when a supervisor later told him “we intimidated him or something like that.”


Each guard said he could not recall if they sounded harsh when they talked to Manning on the way to the exercise room.


They both said that aside from the January incident, Manning was courteous and professional in his interactions with them.  Both described him as an average prisoner, though Tankersly acknowledged that Manning was a high profile detainee who had the attention of high-ranking officials at the base.


“It’s hard to put ‘average’ on such a high profile, when you have higher ups on base come and check through to that see all was OK,” Tankersly said.


Gunnery Sgt. William Fuller, one of the senior officers at the brig, also testified today about his participation in a Classification and Assessment board that routinely assessed whether Manning’s Maximum Custody and Prevention of Injury status should be downgraded. The board never reduced Manning’s status during his stay.


Fuller acknowledged that before the January incident he and another brig official had considered a downgrade because Manning was “doing pretty good.”


He said the Jan. 18incident “kind of reset things … we had to keep him on Prevention of Injury.”


Fuller also cited Manning’s quiet interactions with him as a reason for keeping Manning on that status.


According to Fuller “he wouldn’t communicate … it seemed like he didn’t really want to talk” and that concerned him, given training he had received that being withdrawn could be an indicator of suicidal behavior.


Fuller admitted that the conversations were really just quick interactions to see how Manning was doing..  When asked to provide examples of longer exchanges he had with other prisoners, Fuller provided brief sentences.  That led David Coombs, Manning’s defense attorney to say sarcastically, “so if he’d thrown in more words then he would have classified as a Chatty Patty?”


Manning’s attorneys claim that a protest on Jan. 17 by Manning supporters, at the entrance to the base, may have motivated an aggressive attitude towards the detainee.


Cline recalled other guards “were annoyed” by the protest” because it would close parts of the base and hinder or interrupt how they got home.”  But Tankersly said the protest had no impact on Manning’s treatment.

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Weaver ants help flowers get the best pollinator









































MOST flowers don't want pesky ants hanging around scaring away would-be pollinators. Not so the Singapore rhododendron - the first flower found to recruit ants to chase poor pollinators away.












Francisco Gonzálvez at EEZA, the arid zone experimental station in Almeria, Spain, and colleagues studied flowers frequented by large carpenter bees (Xylocopa) and a much smaller solitary bee, Nomia. The larger bees seemed to be better pollinators - setting far more fruit than the smaller bees.












The team found that Nomia avoided plants with weaver ant patrols, and when they did dare to land, were chased away or ambushed by the ants. Being so much bigger, carpenter bees weren't troubled by the ants (Journal of Ecology, DOI:10.1111/1365-2745.12006).












Plants usually produce chemical repellents to scare off insects that prey on their pollinators. But lab tests suggested Gonzálvez's flowers were actively attracting weaver ants, although how remains a mystery. The team thinks carpenter bees choose flowers with ants so they don't have to compete with Nomia.












Michael Kaspari of the University of Oklahoma in Norman says this is a new kind of plant-ant interaction, and that the team makes a "strong case" for the rhododendron manipulating the behaviour of weaver ants to ward off inefficient pollinators.


















































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State visit to Indonesia reaffirmed bilateral ties: President Tony Tan






SINGAPORE: Singapore President Tony Tan Keng Yam said his state visit to Indonesia has reaffirmed the excellent bilateral relationship between the two countries.

Speaking to Singapore media at the end of his five-day visit, Dr Tan stressed that the strong ties are built on the close people-to-people relationship.

It was President Tony Tan's first state visit to Indonesia but not his first to the country.

Having been to Indonesia many times since the 1970s, President Tony Tan is familiar with many Indonesians, including President Susilo Bambang Yudhoyono, whom he had met 20 years ago when they were both cabinet ministers.

Dr Tan said: "We know each other well. And I've always have a very high respect for President Yudhoyono, (who is) not only a strong leader, but also somebody with a vision -- somebody who is interested in international affairs as well as our bilateral relations. And we have a very good and easy relationship."

Dr Tan also said that he was impressed with the changes and rapid development in the country.

Dr Tan said: "I would consider that Indonesia has gone past the developing country stage. It is now a middle income country. (There's) still a lot to be done but nevertheless you can see evidence of wealth creation everywhere."

Dr Tan attributed much of Indonesia's progress to the leadership of President Yudhoyono, whose term in office has been marked by political stability and economic growth in the country.

During his 5 day visit, the Singapore President interacted with a broad spectrum of people, Indonesians and Singaporeans, professionals and students alike.

And it was seeing the Singapore volunteers working in Indonesia, Dr Tan said, which was the highlight of his visit.

President Tan and his wife were moved by the work done by the Singapore International Foundation for cancer-stricken children.

And were impressed by the efforts of Mercy Relief to help villagers affected by the 2010 Mount Merapi eruptions.

Dr Tan said: "Seeing the volunteers from Indonesia and Singapore working together, talking to them, you know (they're) not just helping people, they themselves are being helped because they feel they are doing something which gives meaning to their lives.

"This is a wonderful spirit of self-help, this spirit of giving. I'm happy that Singaporeans and Singapore institutions can find ways to interact with their Indonesian counterparts and provide help and assistance wherever possible.

"A country is not built on economic values alone. That, is important. But it's all built and strengthen by human relations."

Dr Tan encouraged more Singaporeans to take part in volunteer work in Indonesia.

He believes they would get as much out their work as the Indonesian beneficiaries.

The Singapore President firmly believes more exchanges between the people in two countries should continue.

He said it is important not only for bilateral ties but that also contribute towards building an ASEAN community.

- CNA/lp



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Android-based Ouya game console shipping soon



Early birds get their hands on Ouya after December 28.



(Credit:
Ouya)


Let the gamers,
Android nuts, and open-source geeks rejoice -- the Ouya is shipping on time!


Well, at least the developers' consoles are, that is. Ouya first garnered attention by raising more than $8.5 million on Kickstarter this summer to create an inexpensive, open-source, Android-based game system.


Early supporters of the crowdfunding campaign got first dibs on a finished Ouya for as little as $95, but those aren't scheduled to ship until March. However, the hundreds of folks who ponied up $699 or more for a first-run, rooted developers' system with early SDK access get to experience Christmas twice in the same week when their consoles ship on December 28.


If creators of the Ouya do fulfill their original commitment to ship the dev kits in December, they'll deserve kudos. Plenty of other Kickstarter-funded projects have run into snags meeting original timelines and commitments -- the Pebble watch is now months late on its original ship date and still working out production issues, for example.



Ouya points out that all consoles will actually be dev kits, but the late December batch is a special group that cost more to produce and give big early backers a first crack at working with the platform. The only catch for developers is that at least some part of the game play has to be available for free, be it a demo or the whole shebang.


Ouya is also working on its own ODK (Ouya development kit) that game designers will be able to access. At the same time, Ouya says it's been busy optimizing Android Jelly Bean for gameplay on a large screen.


If Ouya takes off, 2013 could be a year in which a certain segment of the population gets even less exposure to the sun than in the past.


If you missed out on the first Ouya rush, there's still a chance to get in on the ground floor noob level. Ouya is giving away 10 developers' consoles next month.


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Photos: Kilauea Lava Reaches the Sea









































































































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Wild West: Calif. Braces for More Stormy Weather












Northern California is bracing for more stormy weather this weekend after heavy rain and strong winds knocked out power to thousands, delayed flights, tied up traffic and flooded some roadways.



After the second in a series of storms slammed the region Friday, scattered showers are expected Saturday before a third storm strikes Sunday morning, according to the National Weather Service.



A flash flood watch will remain in effect for most of the San Francisco Bay Area and the Santa Cruz Mountains throughout the weekend. The storms could cause rock and mud slides in areas already saturated and affected by wildfires this summer, said NWS forecaster Diana Henderson in Monterey.



"It's not a super storm by any measure, but this is pretty significant," Henderson said. "We should see periods of moderate to heavy rains."



Friday's stormy weather may be behind the death of a Pacific Gas & Electric worker in West Sacramento who was killed after his truck crashed into a traffic signal pole during the stormy weather.



Friday's storm delayed flights at San Francisco International Airport and knocked down a large tree that smashed a car and blocked a busy street for hours in the city's affluent Pacific Heights neighborhood.






AP Photo/The Press Democrat, Kent Porter








The North Bay was seemingly hit the hardest, as parts of Sonoma County received more than 7 inches of rain and areas in Napa County received nearly 6 inches, Henderson said.



With rain expected all weekend long, Tony Negro, a contractor from Penngrove, Calif., in Sonoma County, said he is worried about water flooding his workshop.



"I'm on my way to get some sand bags," he said.



Thousands of people were without power in that area after an outage that also affected the San Francisco-Oakland Bay Bridge. The suspension span of the bridge was briefly in the dark as traffic was backed up longer than usual because of rain and strong wind gusts.



Also, a mudslide shut down a stretch of Highway 84 east of Fremont, the California Highway Patrol reported. There was no estimate on when it would reopen.



In Sacramento, an empty big-rig jackknifed in the southbound lanes and struck the median divider on Interstate 5 south of downtown Friday morning, the CHP said.



"I would definitely say it's weather-related. The reports came in that he hit a water puddle and hydroplaned and couldn't correct," CHP Officer Mike Bradley said. "A lot of high-profile vehicles, especially the lighter ones, are getting windblown and having some problems maintaining their lane."



No one was injured in the crash on I-5, California's main north-south highway. But a second vehicle also was damaged and had to be towed, while workers cleaned up diesel fuel spilled from the tractor-trailer.



In West Sacramento, police say wet conditions may have been a factor when a PG&E worker died after he lost control of his vehicle and slammed into a traffic pole. PG&E workers at the scene told KCRA-TV that the driver had been working overtime and was returning from Clarksburg in Yolo County.



In Los Angeles, conditions were wet and gloomy as downtown skyscrapers disappeared in low-hanging clouds.





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